These days,a considerable amount of advertising is directed at children.Should it be banned because of the adverse effect?To what extent do you agree or disagree?

Out of the 3 reported

cases

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, two were male and one female and all had a similar clinical gingival presentation. Palatal swelling was present in all

three

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cases

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. It has been documented that along with angiotensin-converting enzyme (ACE2)

receptors

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, the CoV-2 can bind to the glucose-regulating protein 78 (GRP78)

receptors

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also

Linking Words

to get entry into the host cells[20].

Therefore

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it can be hypothesized that as glucose-regulating protein 78 (GRP78)

receptors

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are a common link for invasion into the host

defense

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defence

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mechanism by

mucormycosis

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as well as by SARS CoV-2,the increased number of GRP78

receptors

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during

Covid-19

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infection[21], can be a reason leading to surge in

mucormycosis

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cases

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after

Covid-19

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infection. No case has been documented yet describing the gingival presentation of

this

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silent and rare infection in

covid-19

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recovered

patients

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.

This

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paper emphasizes the role of dental surgeons in recognizing the initial symptoms leading to early

diagnosis

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.

This

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otherwise

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neglected

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neglect

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may later lead to a poor prognosis on extension into

rhino-orbital

Correct article usage

the rhino-orbital

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and rhino-cerebral region.

Mucormycosis

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is a medical emergency. Computed tomography (CT) is the cornerstone of modern medical radiology to diagnose the extension of the lesion in the Rhinomaxillary region. Cone-beam Computed tomography (

CBCT

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), which is advanced imaging technology in dentistry, provides images equivalent to medical CT at reduced costs and radiation doses. The radiation dose to the patient with

CBCT

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is 40 % lesser than that of

multi-slice

Correct article usage

the multi-slice

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CT dose.

However

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, the usefulness of

CBCTin

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CBCT in

the

diagnosis

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of

mucormycosis

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may be limited, especially if there are intracranial extensions. Due to the rapidity of invasive infection,

CBCT

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should be immediately advised by

the

Correct article usage

apply

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dental professionals to monitor disease extension, if

mucormycosis

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is suspected in

Covid-19

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recovered

patients

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. Prompt

diagnosis

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, early management, and reversing the underlying risk factors, if possible may improve the prognosis and survival rate of the patient. In all

three

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patients

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,

CBCT

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was advised immediately on suspecting

mucormycosis

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based on history and clinical findings. As all

three

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CBCTs’ revealed

unusual

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unusually

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massive bone destruction, a provisional

diagnosis

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of

mucormycosis

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was made and the

patients

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were immediately referred to the emergency medicine department.

Further

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detailed investigations by the medicine and ENT department confirmed

mucormycosis

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as the final

diagnosis

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. Surgical management

also

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should be initiated early in the course of treatment.

This

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should involve

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debridement

Correct article usage

the debridement

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of all infected tissues.

Debridement

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is commonly defined as the process of removing necrotic and devitalized tissue. The presence of necrotic tissue within a wound may impair wound repair processes by stimulating inflammation and delaying granulation and epithelialization. Several methods for

debridement

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may be employed, including surgical, enzymatic, mechanical, autolytic, and surgical, along with systemic antifungals. Survival rates among

patients

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with invasive sinus involvement without cerebral involvement may be as high as 50-80%[22].

Amphotericin

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B

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is the antifungal agent of choice. It is a polyene antifungal agent that acts by binding to sterols (primarily ergosterol) in the fungal cell membrane with a resultant change in membrane permeability. Combined treatment of thorough

debridement

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and

amphotericin

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B

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has a survival rate of 80%[14]. Lipid complex

Amphotericin

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B

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is a formulation designated to be less nephrotoxic than conventional

Amphotericin

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B

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[23]. Other antifungals used against Mucorales are posaconazole and Isavuconazole[23,24,25]. Early surgical

debridement

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and management due to timely

diagnosis

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of

mucormycosis

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prevented the

further

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fungal spread and aggressive treatment in all

three

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of the

cases

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reported.