IELTS Writing Samples Band 2

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At 100nM, cisapride cut both the outward and tail currents in HERG cells (1A-1B). The control trace peaked near + 10 mV, bent slightly before the tail at - 50mV (1A), then fell once the drug was added. “Cisapride suppressed both currents,” the authors wrote. Control cells (1C) barely moved, and the current voltage plots (1D-1E) showed activation near -40mV with lower current after treatment. After that, as shown in Figure 2, the blocked came only after activation; the first pulse looked normal, with” little closed-state block,” but the current then fell during depolarization and almost returned after washout. Next, the dose data (3) gave an IC50 of 6.5nM. At different voltages, the last plot (4A-B) showed stronger block at higher voltage reaching almost 90% at +20 mV, linked to the open state of the channel.
The team built the HERG gene inside a pCDNA3 vector and passed it into HEK293 cells with lipofectamine. Shortly, a single line that showed clear electrical signals was chosen after G-418 treatment, lifted with trypsin, and tested within hours. From here, the cells were placed under an inverted microscope in a buffered setup. There, membrane currents were noted in a whole-cell configuration by suction pipettes and read with a patch-clamp amplifiers. It’s worth noting that crisapride of 99.8% purity was dissolved in pure ethanol to make 1 5mM sock, and the ethanol group at 0.01% had no effect on HERG current. Data were given as a mean ± SE, with significance tested by Student’s t-test and permutation analysis.
In some countries, their has been a growing trend where parents decide to homeschool their children, rarther than sending them to school. In this essay, we'll see if the advantages outweight the disadvantages.
To solve the environmental related problems, a number of effort has made by many nations, but still the situation is same. The main reasons for these issues is usage of plastic bags and vehicle emissions. To solve these problems, people can give more preference to recyling and eco-friendly process.
Fig.1A-C show tirzepatide in open regions of the brain, notably the area postrema and NTS, both linked to appetite control. Then Fig. 2A-C point to activity in the NST, PBN and CeA, where GLP-1R and GIPR seem to act together there. Once GLP-1R is taken out of the brainstem (Fig. 3A-C), the effect fades, so these lower parts seem to drive the change. After that, Fig. 4A shows GIPR in red in the area postrema, close to GABA cells that quiet nearby GLP-1R neurons. Finally, in the later Figures (5-7), the CeA is clearer; these cells tie to feeding centers, and when silent, the shared effect drops away, so the CeA feels like the core of it all.
In recent years, many countries have decided to allow smoking in public places.I strongly agree because it's common to inhale someone else's smoke by mistake,which will harm you more than him.In this essay, I'll explain why i agree with this information.
In many cities today, since most people live in large apartment block, they fase some challenges.
Firstly, some companies offer, boring and ugly uniforms. As a result, some people working there will dislike going to their jobs. Imagine wearing the same outfit every day. Personally, would never wear the same uniform every day, considering you'll be there for a long time.
There is a common recognition that it is better for workers to shorten the working week while the weekend should be extended.
The line graph illustrates the mean release of carbon dioxide per individual in four countries from 1967 to 2007.
The maps illustrate the main changes that have taken place at the Porth Harbour between 2000 and the present day.
In my opinion, i think it is the best way nowadays. Overall, this method can differ employees more quickly. It can differ people that has vary certification, diploma, abilities and so on. such as some reputioned companies, the personnel will receive resumes and consult several and critical questions.
In recent years, there has been a huge increase in the number of individuals about using job interviews before offering a job position. I firmly believe that basic interview and job tasks have to be combined. From my perspective, having combined job interviews are the best way to offer a position to others, but it should be developed related to practical work.
Many people believed that the teengers should be baying attention to all subjects equally. While thers, think they most only focus on the matiral they are best at or preffered subject only. In my opinion, I believe that students should be covering all subjects to have clear clue about various soureces of knowledge.
The authors use gene targeting in mouse embryonic stem cells where most of the β1-AR coding region is replaced with a neomycin cassette. From this step come the knockout mice, shown by Southern blot and Western blot that the gene change is properly made and the β1-protien is no longer present. The study then looked at the heart, where its signals and rhythm are checked by 125I-CYP binding, adenylate cyclase assays, catheter recordings, and isolated heart tests with isoproterenol, so the heart’s response to the loss of β1-AR is seen more clearly.
It's crucial to improved the road safety, increase tne minimum permitted age for driving is not a sloution. Due to the streets should have all the actorse for the safety.
It is thought by the few that the authorities is fritteting income on the crafts, instead it can be used for other productive things. In my opinion, I disagree that public sector should neglate the public talent, they should be valued equal as other athlets.
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