Natural product chemistry plays a crucial role in the field of drug development and the unprecedented growth of the pharmaceutical industry. Nature produces the best possible chemical structure in her niche, but credit also goes to scientists who could identify complex and diverse intangible architecture and potential biological activity of these molecules. Sometimes, these useful wonders are not sufficient in amount to serve civilization; however, they work as lead molecules to synthesize in the laboratories to treat life-threatening diseases. There are various diseases to deal with, but inflammation is a precursor for many of them. Thus, it was worthwhile to work on anti-inflammatory compounds with a novel and prominent therapeutic target of neutrophils.