Mucormycosis is an angio-invasive fungal infection caused by the fungi belonging to the order Mucorales. The Mucorales can cross physical barriers and invade host defence mechanisms mainly in immunocompromised individuals. Human infection is said to be caused by asexual spore formation which then becomes airborne and resides on the oral and nasal mucosa of humans. In the vast majority of immunologically competent hosts, these spores are contained by the host phagocytic response. However, if host defence fails, germination follows by hyphae development. It progresses as the hyphae begin to invade vessel walls and arteries causing thrombosis and ischemia of the affected tissues. Fungal hyphae produce a substance called Rhizoferrin (Siderophores), which binds to iron available in the blood circulatory system. This Iron-Rhizoferrin complex is responsible for the fungus growth and its intracellular processes. It has been documented that R. arrhizus adheres directly to the vascular endot...